Background and Aim: Thyroid cancer incidence has been increasing in Saudi Arabia, with variation by age and sex. This study aimed to evaluate the association of age and sex with clinicopathologic characteristics and outcomes of thyroid cancer.
Methods: We conducted a retrospective medical record review of adult patients with confirmed thyroid cancer diagnosed and/or treated at King Abdulaziz University Hospital, Jeddah, between January 2010 and December 2023. Demographic data, tumour characteristics, treatment, and outcomes were extracted. Statistical analyses were performed using SPSS version 26.
Results: Among 331 patients, papillary carcinoma was the most common histologic subtype. Older age at diagnosis was associated with more advanced stage, larger tumour size, and documented distant metastasis. Male patients were older at diagnosis and had larger tumours, and sex was associated with lymph node metastasis and invasion of adjacent structures.
Conclusion: In this single-center retrospective cohort, age and sex were associated with thyroid cancer characteristics and selected outcomes. These findings support considering age and sex when interpreting disease extent and planning follow-up, while recognizing the limitations of retrospective observational data.
KW: Thyroid cancer, Papillary thyroidcarcinoma, Age, Sex, Metastasis UL https://dawnmed.com.sa/../abstract?article_id=7